Bence Jones Proteins are monoclonal kappa or lambda immunoglobulin light chains with relatively low molecular weight which pass into the urine and are nephrotoxic. They are produced by neoplastic plasma cells. This test is used in the diagnosis of multiple myeloma. HIGH levels of Bence Jones Proteins in urine are found in the context of end-organ manifestations such as malignant bone marrow cancer, renal failure, lytic bone disease, anemia, or large number of plasma cells. See Kappa and Lambda Light Chains, 24 Hrs Urine
Transfer two 4 mL aliquots from a well-mixed urine
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