Anti-Hu is associated with small cell lung cancer. Anti-Ri is associated with neuroblastoma (children) and fallopian tube or breast cancer (adults). Anti-Yo is associated with ovarian and breast carcinomas. The presence of one or more of these antibodies supports the clinical diagnosis of paraneoplastic syndrome and leads to a focused search for underlying neoplasm. These markers aid in the discrimination between true paraneoplastic disorders and other inflammatory disorders of the nervous system.
Allow specimen to clot completely at room temperature. Separate from cells ASAP
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