D-Dimer is a byproduct of fibrinolysis; it is a small protein fragment present in the blood after a blood clot is degraded. D-dimer testing is of clinical use when there is a suspicion of DVT (Deep Venous Thrombosis), which causes swelling, pain, and tissue damage, or PE (Pulmonary Embolism). In patients suspected of DIC (Disseminated Intravascular Coagulation), d-dimers may also aid in the diagnosis, and to monitor the effectiveness of treatment. HIGH levels of D-dimers are indicative of excessive fibrinolysis, i.e. abnormally active coagulation (ex: DIC), but it may also be due to a recent surgery, trauma, or infection. Elevated levels are also seen with liver disease, pregnancy, eclampsia, heart disease, and some cancers.
Centrifuge within one hour of collection. Transport under ice.
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