Anti Mitochondrial Antibodies (AMA) are autoantibodies of the IgG class directed against components of the mitochondria. This test is an early marker for primary biliary cirrhosis (PBC), a cholestatic disease which mainly affects middle-aged women. This disease usually begins insidiously and manifests as pruritis and jaundice. Low levels of AMA are also found in chronic active hepatitis. See also Nuclear Antibodies, Smooth Muscle Antibodies, and Autoimmune Liver Antigen Profile.
Separate serum from cells ASAP or within 2 hours of collection
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