Nitroblue tetrazolium test is a blood test that measures the ability of the immune system to convert the colorless nitroblue tetrazolium (NBT) to a deep blue. This test is performed as a screen for chronic granulomatous disease (CGD). If an individual has CGD, the white cells in their blood will not turn blue when exposed to the NBT. Chronic Granulomatous Disease is an inherited disorder characterized by a defect in which neutrophils (white blood cells in the body that kill invading bacteria or fungus) are unable to kill certain microorganisms. Therefore, Nitroblue Tetrazolium is DECREASED in chronic granulomatous disease. INCREASED NBT might be associated with bacterial infections, myeloid leukemia, trauma, and acute infarction.
Early Morning sample , Sample should be sent to Consulting lab – Khalidi Hospital Before 10 AM .
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