Pyridinoline and deoxypyridinoline are two major cross linking molecules (DPD) which play a role in determining the characteristics of collagen. Pyridinoline is a fluorescent cross-linking compound of collagen fibers. It is present in collagen of bone and cartilage, but is absent in collagen of skin. It is not present in newly synthesized collagen and is formed from aldimine cross-links during maturation of collagen fibers. Pyridinoline and deoxypyridinoline were found to be released into the blood during bone degradation and rapidly excreted in the urine. Both these compounds were proposed as a marker for metastatic bone tumor in patients with prostate cancer.
5 mL 2nd Early morning urine Refrigerated
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