18-Hydroxycorticosterone is a derivative of corticosterone, and serves as an intermediate in the synthesis of Aldosterone by the enzyme aldosterone synthase. It acts on the kidney, gut, salivary glands, sweat glands, vascular endothelium and the brain. Elevated levels are associated in patients with adrenal tumors, congenital adrenal hyperplasia, Cushing’s syndrome, hypertension, edema, and hypokalemia. Low levels are associated with weight loss, hypotension, and hyperkalemia. See also Aldosterone, Serum.
Refrigerated 2 mL Serum or EDTA PLasma
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